Cells 'sense' physical forces to seal tissues and protect organs

Northwestern Medicine scientists have uncovered a molecular mechanism that enables cells to protect organs from leaks, infection and inflammation, according to a study published in the Journal of Cell Biology. The findings of the study add to scientific understanding of how epithelial cells maintain protective barriers, said senior author Cara J. Gottardi, professor of medicine in the Division of Pulmonary and Critical Care and of cell and developmental biology.